Researchers at Johns Hopkins University have purchased a nano 25^TM 8-channel nano-volume robotic pipettor for use in PCR optimization and sequencing reaction miniaturization research. The nano 25 was selected by Johns Hopkins due to its ability to incorporate a unique closed-loop, pressure-based feedback system that assures precise, verifiable transfers of liquid volumes, and Hudson's SoftLinx^TM scheduling software, which provides an easy-to-use interface to coordinate the nano 25's operation with other instruments. Also, it has the ability to automatically make "on the fly" adjustments to compensate for variations in temperature, viscosity and residual volume to ensure accuracy. The nano 25's automated diagnostics can also detect and correct clogging, self-calibrate on every pipetting cycle and give real-time verification of every volume dispensed. The nano 25 is also compatible with robot loading systems from most manufacturers, including Hudson Control's own PlateCrane EX®, and can be used in-line with Hudson Control's Lablinx® high-throughput track system for unparalleled high-throughput and ease of use.