The workcells in this new category are being designed to allow researchers in the drug discovery field to run a wide range of useful assays that are typically used in high-throughput screens. The various options available in the VaryScreen series support many cell-based, receptor-based and enzyme-based assays using common detection methods, such as fluorescence energy transfer, reporter gene luminescence, enzyme-linked immunoabsorption, and UV-Visibile light absorption. With the accompanying SoftLinx control software, it is possible to design complex assays with flow schemes that can vary as the nature of the results are obtained and examined interactively.
Hudson Control Group introduces the VaryScreen I - an all-new versatile assay screening and development system for research in high throughput environments:
- Conduct multiple assay types on a single workcell: ALPHA Screens, UV/Vis Absorbance, Fluorescence Polarization, Luminescence, FRET and ELISA, and others.
- Flexibility for on-the-fly assay development
Easily develop new assays, model protocols, optimize conditions and validate results. >> more
Hudson’s RapidHit Simultaneous Automated HitPicking System is a compact, self-contained system that allows users to obtain assay plates comprised of the actual hits detected in a primary screen using the same compound source plates that provided the primary screen. The RapidHit uses the output files produced by the plate reader as they become available, and automatically selects and transfers “hits” based on user-entered criteria. As each primary screen assay plate is finished, the RapidHit immediately moves the hits to a secondary assay “hit plate," and completely eliminates the possibility of receiving the wrong compounds in secondary screening plates.
Hudson's new VaryScreen ADME-Tox System is a all-in-one system that is ready, out of the box, to run many of the necessary screens typically used to determine the pharmaceutical profile of a potential drug candidate. It contains liquid handling robots to setup plates for each of the required protocols, and several microplate handlers to store and transport the plates between the liquid handlers, incubator and multi-mode reader. The system comes with a number of built-in standard protocols to help the user get their profiling up and running as quickly as possible.