Message From Phil Farrelly, President

Miniaturized Bioreactor System May Revolutionize Cell Growth Studies

A major pharmaceutical company has contracted with Hudson to automate the process of optimizing cell-line growth prior to scale-up for production. This unique system will fully-automate the sampling, feeding and monitoring of a novel, miniaturized bioreactor that supports 24 separate growth reactions in the space of a single microplate  footprint. This system, which will run unattended for 5 to 7 days at a time, controls 24 individual vessels where each vessel’s cells are grown under their own, individual process protocol. Each vessel has its own unique process, including set points for time, oxygen level control, sampling and feeding rates, NH3/CO2 levels, etc. These are all monitored and adjusted by Hudson’s powerful SoftLinx scheduling software.

The entire system, including sample plate-handling, media feeding and cell sampling  instruments, fits in a standard fume hood, affording complete sterility and safety. This
extraordinarily compact system can replicate the functions of the large, room-sized  systems that are commonly used for cell-growth optimization studies. It dramatically reduces the cost and effort ordinarily required for cell growth optimization, and, with its full, unattended automation, should revolutionize the way researchers throughout industry perform this important task.